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VEGFR inhibitor OSI-930, Purity ≥98%
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Cat. No.: X24-06-ZQ250

VEGFR inhibitor OSI-930, Purity ≥98%

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Synonym: 728033-96-3; VEGFR inhibitor; OSI930

  • CAS Number: 728033-96-3
  • Compound CID: 9868037
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Product Size
5 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
OSI-930, soluble in DMSO and ethanol and insoluble in water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against VEGFR. It targets CSF-1R, KDR, Abl, Aurora A, Axl, C-Raf, CDK2/CyclinA, EGFR, FLT1, FLT3, and IKKβ.
Molecular Weight
443.4
Molecular Formula
C22H16F3N3O2S
Targets
CSF-1R: 15 nM; KDR: 9 nM; Abl: 4.738 μM; AuroraA: >10 μM; Axl: >10 μM; C-Raf: 41 nM; CDK2/CyclinA: >10 μM; EGFR: >10 μM; FLT1: 8 nM; FLT3: 1.303 μM; IKKβ: >10 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 85 mg/mL (191.68 mM); Water: Insoluble; Ethanol: 3 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
VEGFR inhibitor OSI-930 is employed to understand the inhibition of VEGFRs, important for developing anti-cancer strategies targeting tumor blood supply.
Publications
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