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VEGFR inhibitor Vatalanib 2HCl, Purity ≥98%
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Cat. No.: X24-06-ZQ271

VEGFR inhibitor Vatalanib 2HCl, Purity ≥98%

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Synonym: 212141-51-0; VEGFR inhibitor; Vatalanib; PTK787; PTK/ZK

  • CAS Number: 212141-51-0
  • Compound CID: 22386467
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Product Size
10 mg; 50 mg; 100 mg; 200 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Vatalanib 2HCl, soluble in DMSO, water and ethanol, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against VEGFR. It targets VEGFR1/FLT1, VEGFR2/Flk1, c-Fms, c-Kit, PDGFRβ, VEGFR2/KDR, and VEGFR3/FLT4.
Molecular Weight
419.7
Molecular Formula
C20H17Cl3N4
Targets
VEGFR1/FLT1: 77 nM; VEGFR2/Flk1: 270 nM; c-Fms: 1.4 μM; c-Kit: 730 nM; PDGFRβ: 580 nM; VEGFR2/KDR: 37 nM; VEGFR3/FLT4: 660 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 77 mg/mL (183.45 mM); Water: 9 mg/mL (21.44 mM); Ethanol: 5 mg/mL (11.91 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Vatalanib 2HCl is employed in research to block VEGFR, crucial for understanding its role in tumor angiogenesis and growth.
Publications
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