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VEGFR inhibitor XL184 free base, Purity ≥98%

Cat. No.: X24-06-ZQ065

VEGFR inhibitor XL184 free base, Purity ≥98%

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Synonym: 849217-68-1; VEGFR inhibitor; BMS-907351

  • MDL: MFCD20926324
  • CAS Number: 849217-68-1
  • Compound CID: 25102847
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
XL184 free base, soluble in DMSO and insoluble in ethanol and water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against VEGFR. It targets Flt-1, Flt-4, and VEGFR2.
Molecular Weight
501.5
Molecular Formula
C28H24FN3O5
Targets
Flt-1: 12 nM; Flt-4: 6 nM; VEGFR2: 0.035 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 92 mg/mL (183.44 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
XL184 free base inhibits VEGFR and is used to explore anti-angiogenic therapy in oncology.
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Blood Group and Lewis Antigen
Blood group A trisaccharide (Cat#: XCO0060Q) Blood group B trisaccharide (Cat#: XCO0068Q) Blood group H disaccharide (Cat#: XCO0074Q) Lewis A trisaccharide (Cat#: XCO0079Q) 3'-Sulfated lewis A (Cat#: XCO0080Q) Lewis B tetrasaccharide (Cat#: XCO0083Q) Lewis X trisaccharide (Cat#: XCO0085Q) Lewis Y tetrasaccharide (Cat#: XCO0088Q)
Human Milk Oligosaccharides (HMOs)
Lacto-N-biose (Cat#: XCO0089Q) 2'-Fucosyllactose (Cat#: XCO0091Q) 3-Fucosyllactose (Cat#: XCO0092Q) Lactodifucotetraose (Cat#: XCO0093Q) Lacto-N-triose I (Cat#: XCO0094Q) 3'-Sialyllactose sodium salt (Cat#: XCO0096Q) 6'-Sialyllactose sodium salt (Cat#: XCO0098Q) 3'-Sialyl-3-fucosyllactose (Cat#: XCO0100Q)
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Dextran
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