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Bcl-2 inhibitor TW-37, Purity ≥98%
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Cat. No.: X23-10-ZQ004

Bcl-2 inhibitor TW-37, Purity ≥98%

Synonym: 877877-35-5; N-[4-(2-tert-Butylphenylsulfonyl)phenyl]-2,3,4-trihydroxy-5-(2-isopropylbenzyl)benzamide; tw 37; N-(4-((2-(tert-Butyl)phenyl)sulfonyl)phenyl)-2,3,4-trihydroxy-5-(2-isopropylbenzyl)benzamide; Bcl-2 inhibitor

  • MDL: MFCD17010275
  • CAS Number: 877877-35-5
  • Compound CID: 11455910
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
TW-37, soluble in DMSO and ethanol and insoluble in water, specifically inhibits the function of the anti-apoptotic proteins, thereby promoting apoptosis in cancer cells. It targets Mcl-1, Bcl-2, and Bcl-xL.
Molecular Weight
573.7
Molecular Formula
C33H35NO6S
Targets
Mcl-1: 0.26 μM (Ki); Bcl-2; Bcl-xL: 1.11 μM (Ki)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 110 mg/mL (191.73 mM); Water: Insoluble; Ethanol: 4 mg/mL (6.97 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
TW-37 can be used to research inducing apoptosis in various tumor types, including pancreatic cancer, multiple myeloma, and prostate cancer.
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