AMD 070 is an active small molecule compound that mediates the CXCR signaling pathway. It targets 125I-SDF-CXCR4, HIV1 (NL4.3 strain), HIV1 (NL4.3 strain), HIV-1 (NL4.3 strain), and HIV-1 (NL4.3 strain).
Molecular Weight
349.5
Molecular Formula
C21H27N5
Targets
125I-SDF-CXCR4: 13 nM; HIV1 (NL4.3 strain): 1 nM (In MT4 cells); HIV1 (NL4.3 strain): 9 nM (In PBMCs); HIV-1 (NL4.3 strain): 3 nM (In MT-4 cells); HIV-1 (NL4.3 strain): 26 nM (In PBMCs) :
Form
Lyophilized powder
Purity
≥98%
Identity
Confirmed by NMR/HPLC/MS.
Applications
AMD 070 can be used to study its function as an HIV entry inhibitor targeting the CXCR4 receptor.
Publications
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Publications
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