Cat. No.: X23-10-ZQ520
CXCR inhibitor AMD 070, Purity ≥98%
Synonym: AMD-070; 558447-26-0; Mavorixafor; (S)-N1-((1H-Benzo[d]imidazol-2-yl)methyl)-N1-(5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine; CXCR inhibitor
- MDL: MFCD11977316
- CAS Number: 558447-26-0
- Compound CID: 11256587
Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
AMD 070 is an active small molecule compound that mediates the CXCR signaling pathway. It targets 125I-SDF-CXCR4, HIV1 (NL4.3 strain), HIV1 (NL4.3 strain), HIV-1 (NL4.3 strain), and HIV-1 (NL4.3 strain).
Molecular Formula
C21H27N5
Targets
125I-SDF-CXCR4: 13 nM; HIV1 (NL4.3 strain): 1 nM (In MT4 cells); HIV1 (NL4.3 strain): 9 nM (In PBMCs); HIV-1 (NL4.3 strain): 3 nM (In MT-4 cells); HIV-1 (NL4.3 strain): 26 nM (In PBMCs) :
Identity
Confirmed by NMR/HPLC/MS.
Applications
AMD 070 can be used to study its function as an HIV entry inhibitor targeting the CXCR4 receptor.
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