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Cat. No.: X23-10-ZQ550

CXCR inhibitor Reparixin, Purity ≥98%

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Synonym: Reparixin; 266359-83-5; DF 1681Y; (R)-2-(4-Isobutylphenyl)-N-(methylsulfonyl)propanamide; DF1681Y; Reparixin (Repertaxin); CXCR inhibitor

  • MDL: MFCD18633292
  • CAS Number: 266359-83-5
  • Compound CID: 9838712
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Reparixin, soluble in DMSO and ethanol and insoluble in water, targets the chemokine receptors CXCR, which are part of the GPCR family. It targets CXCR1, CXCR1-Ile43Val, CXCR1-wt, and CXCR2.
Molecular Weight
283.39
Molecular Formula
C14H21NO3S
Targets
CXCR1: 1 nM; CXCR1-Ile43Val: 80 nM (In L1.2 cells); CXCR1-wt: 5.6 nM (In L1.2 cells); CXCR2: 100 nM (In cells)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 52 mg/mL (183.49 mM); Water: Insoluble; Ethanol: 52 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
Reparixin can be used to study its effects as a CXCR1/2 inhibitor in inflammation and cancer research.
Publications
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