Reparixin, soluble in DMSO and ethanol and insoluble in water, targets the chemokine receptors CXCR, which are part of the GPCR family. It targets CXCR1, CXCR1-Ile43Val, CXCR1-wt, and CXCR2.
Molecular Weight
283.39
Molecular Formula
C14H21NO3S
Targets
CXCR1: 1 nM; CXCR1-Ile43Val: 80 nM (In L1.2 cells); CXCR1-wt: 5.6 nM (In L1.2 cells); CXCR2: 100 nM (In cells)
Reparixin can be used to study its effects as a CXCR1/2 inhibitor in inflammation and cancer research.
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