Cat. No.: X23-10-ZQ550
CXCR inhibitor Reparixin, Purity ≥98%
Synonym: Reparixin; 266359-83-5; DF 1681Y; (R)-2-(4-Isobutylphenyl)-N-(methylsulfonyl)propanamide; DF1681Y; Reparixin (Repertaxin); CXCR inhibitor
- MDL: MFCD18633292
- CAS Number: 266359-83-5
- Compound CID: 9838712
Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
Reparixin, soluble in DMSO and ethanol and insoluble in water, targets the chemokine receptors CXCR, which are part of the GPCR family. It targets CXCR1, CXCR1-Ile43Val, CXCR1-wt, and CXCR2.
Molecular Formula
C14H21NO3S
Targets
CXCR1: 1 nM; CXCR1-Ile43Val: 80 nM (In L1.2 cells); CXCR1-wt: 5.6 nM (In L1.2 cells); CXCR2: 100 nM (In cells)
Solubility
DMSO: 52 mg/mL (183.49 mM); Water: Insoluble; Ethanol: 52 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
Reparixin can be used to study its effects as a CXCR1/2 inhibitor in inflammation and cancer research.
Related Products
Quick Links
