Cat. No.: X23-10-ZQ571
CXCR inhibitor AMD3100, Purity ≥98%
Synonym: Plerixafor; 110078-46-1; Mozobil; AMD3100; 1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene; Amd 3100; CXCR inhibitor
- MDL: MFCD05662218
- CAS Number: 110078-46-1
- Compound CID: 65015
Product Size
10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
AMD3100, soluble in warmed water and ethanol and insoluble in DMSO, targets the chemokine receptors CXCR, which are part of the GPCR family. It targets CXCL12 mediated chemotaxis and CXCR4.
Molecular Formula
C28H54N8
Targets
CXCL12 mediated chemotaxis: 5.7 nM; CXCR4: 44 nM
Solubility
DMSO: Insoluble; Warmed water: 3 mg/mL (5.96 mM); Ethanol: 86 mg/mL (171.05 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
AMD3100 can be used to investigate its effects as a CXCR4 antagonist in stem cell mobilization and HIV research.
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