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DNA-PK inhibitor LTURM34, Purity ≥98%
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Cat. No.: X24-05-ZQ233

DNA-PK inhibitor LTURM34, Purity ≥98%

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Synonym: 1879887-96-3; LTURM 34; LTURM-34; DNA-PK inhibitor

  • CAS Number: 1879887-96-3
  • Compound CID: 122705987
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
LTURM34, soluble in DMSO and ethanol and insoluble in water, impairs the non-homologous end joining (NHEJ) pathway of DNA repair, thereby sensitizing cancer cells to treatments that induce DNA double-strand breaks. It targets DNA-PK, PI3Kβ, and PI4Kδ.
Molecular Weight
414.48
Molecular Formula
C24H18N2O3S
Targets
DNA-PK: 34 nM; PI3Kβ: 5.8 nM; PI4Kδ: 8.5 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 81 mg/mL (195.42 mM); Water: Insoluble; Ethanol: 4 mg/mL (9.65 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
LTURM34 can be used to study its selective inhibition of specific signaling pathways involved in cancer progression.
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