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DNA-PK inhibitor Nedisertib, Purity ≥98%
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Cat. No.: X24-05-ZQ234

DNA-PK inhibitor Nedisertib, Purity ≥98%

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Synonym: 1637542-33-6; MSC2490484A; MSC-2490484A; MSC 2490484A; M3814; M-3814; M 3814; DNA-PK inhibitor

  • CAS Number: 1637542-33-6
  • Compound CID: 86292849
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Nedisertib, soluble in DMSO and ethanol and insoluble in water, impairs the non-homologous end joining (NHEJ) pathway of DNA repair, thereby sensitizing cancer cells to treatments that induce DNA double-strand breaks.
Molecular Weight
481.91
Molecular Formula
C24H21ClFN5O3
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 86 mg/mL (178.45 mM); Water: Insoluble; Ethanol: 2 mg/mL (4.15 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Nedisertib is utilized in research to study its inhibition of DNA-PK and PI3K in cancer therapy.
Publications
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