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DNA-PK inhibitor NU7026, Purity ≥98%
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Cat. No.: X24-05-ZQ235

DNA-PK inhibitor NU7026, Purity ≥98%

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Synonym: 154447-35-5; NU 7026; NU-7026; DNA-PK inhibitor

  • CAS Number: 154447-35-5
  • Compound CID: 9860529
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
NU7026, soluble in DMSO and insoluble in ethanol and water, impairs the non-homologous end joining (NHEJ) pathway of DNA repair, thereby sensitizing cancer cells to treatments that induce DNA double-strand breaks. It targets ATM, ATR, DNA-PK, and PI3K.
Molecular Weight
281.31
Molecular Formula
C17H15NO3
Targets
ATM: >100 μM; ATR: >100 μM; DNA-PK: 0.23 μM; PI3K: 13 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 1 mg/mL (3.55 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
NU7026 can be used to investigate its role as a DNA-PK inhibitor and its impact on cell cycle regulation and cancer cell survival.
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