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EGFR-HER2 inhibitor AG-18, Purity ≥98%
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Cat. No.: X24-05-ZQ658

EGFR-HER2 inhibitor AG-18, Purity ≥98%

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Synonym: 118409-57-7; RG-50810; RG-50858; TX 825; Tyrphostin 23; Tyrphostin A23; Tyrphostin AG-18; EGFR-HER2 inhibitor

  • CAS Number: 118409-57-7
  • Compound CID: 2052
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Product Size
25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AG-18, soluble in DMSO and ethanol and insoluble in water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR.
Molecular Weight
186.17
Molecular Formula
C10H6N2O2
Targets
EGFR: 35 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 34 mg/mL (182.63 mM); Water: Insoluble; Ethanol: 34 mg/mL (182.63 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
AG-18 can be used to study its effects as an inhibitor of FGFR1 tyrosine kinase in cancer and angiogenesis research.
Publications
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