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EGFR-HER2 inhibitor AST-6, Purity ≥98%
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Cat. No.: X23-10-ZQ1029

EGFR-HER2 inhibitor AST-6, Purity ≥98%

Synonym: 1050500-29-2; Allitinib tosylate; AST-1306 TsOH; AST-6; AST-1306 (TsOH); N-[4-[3-Chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]prop-2-enamide; 4-methylbenzenesulfonic acid; EGFR-HER2 inhibitor

  • CAS Number: 1050500-29-2
  • Compound CID: 25027665
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
AST-6, soluble in DMSO and insoluble in ethanol and water, is a potent and specific inhibitor of the tyrosine kinase activity of EGFR. It targets ErbB2, ErbB4, Abl, and Akt1.
Molecular Weight
621.1
Molecular Formula
C24H18ClFN4O2.C7H8O3S
Targets
ErbB2: 3.0 nM; ErbB4: 0.8 nM; Abl: >10 μM; Akt1: >10 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 115 mg/mL (185.16 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
AST-6 can be used to inhibit receptor tyrosine kinases, aiding in cancer research.
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