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EGFR-HER2 inhibitor AV-412, Purity ≥98%

Cat. No.: X23-10-ZQ1049

EGFR-HER2 inhibitor AV-412, Purity ≥98%

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Synonym: AV-412; 451493-31-5; AV-412 Tosylate; MP-412; AV412; 451493-31-5 (tosylate); EGFR-HER2 inhibitor

  • CAS Number: 451493-31-5
  • Compound CID: 11700696
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Product Size
2 mg; 5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AV-412 is a potent and specific inhibitor of the tyrosine kinase activity of EGFR. It targets EGFR, EGFR (L858R), EGFR (L858R/T790M), and EGFR(T790M).
Molecular Weight
851.4
Molecular Formula
C27H28ClFN6O.2C7H8O3S
Targets
EGFR: 0.75 nM; EGFR (L858R): 0.5 nM; EGFR (L858R/T790M): 2.3 nM; EGFR (T790M): 0.79 nM
Form
Lyophilized powder
Purity
≥98%
Identity
Confirmed by NMR/HPLC/MS.
Applications
AV-412 can be used to inhibit EGFR and HER2 for research into cancer therapy.
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Blood Group and Lewis Antigen
Blood group A trisaccharide (Cat#: XCO0060Q) Blood group B trisaccharide (Cat#: XCO0068Q) Blood group H disaccharide (Cat#: XCO0074Q) Lewis A trisaccharide (Cat#: XCO0079Q) 3'-Sulfated lewis A (Cat#: XCO0080Q) Lewis B tetrasaccharide (Cat#: XCO0083Q) Lewis X trisaccharide (Cat#: XCO0085Q) Lewis Y tetrasaccharide (Cat#: XCO0088Q)
Human Milk Oligosaccharides (HMOs)
Lacto-N-biose (Cat#: XCO0089Q) 2'-Fucosyllactose (Cat#: XCO0091Q) 3-Fucosyllactose (Cat#: XCO0092Q) Lactodifucotetraose (Cat#: XCO0093Q) Lacto-N-triose I (Cat#: XCO0094Q) 3'-Sialyllactose sodium salt (Cat#: XCO0096Q) 6'-Sialyllactose sodium salt (Cat#: XCO0098Q) 3'-Sialyl-3-fucosyllactose (Cat#: XCO0100Q)
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Cyclodextrin
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Dextran
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