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EGFR-HER2 inhibitor AZD8931, Purity ≥98%
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Cat. No.: X23-10-ZQ1030

EGFR-HER2 inhibitor AZD8931, Purity ≥98%

Synonym: Sapitinib; 848942-61-0; AZD8931; AZD-8931; AZD8931 (Sapitinib); 2-(4-((4-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)-N-methylacetamide; EGFR-HER2 inhibitor

  • MDL: MFCD18385011
  • CAS Number: 848942-61-0
  • Compound CID: 11488320
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
AZD8931, soluble in DMSO and insoluble in ethanol and water, is a potent and specific inhibitor of the tyrosine kinase activity of EGFR. It targets EGFR, ErbB2, and ErbB3.
Molecular Weight
473.9
Molecular Formula
C23H25ClFN5O3
Targets
EGFR: 4 nM; ErbB2: 3 nM; ErbB3: 4 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 37 mg/mL (78.07 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
AZD8931 is studied for its inhibitory effects on EGFR and HER2 signaling in cancer models.
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