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EGFR-HER2 inhibitor BIBW2992, Purity ≥98%
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Cat. No.: X23-10-ZQ1031

EGFR-HER2 inhibitor BIBW2992, Purity ≥98%

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Synonym: Afatinib; 439081-18-2; 850140-72-6; Tovok; BIBW2992; Tomtovok; BIBW 2992; EGFR-HER2 inhibitor

  • MDL: MFCD12407405
  • CAS Number: 439081-18-2
  • Compound CID: 10184653
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
BIBW2992 is a potent and specific inhibitor of the tyrosine kinase activity of EGFR. It targets EGFR (L858R), EGFR (L858R/T790M), EGFR (wt), and HER2.
Molecular Weight
485.9
Molecular Formula
C24H25ClFN5O3
Targets
EGFR (L858R): 0.4 nM; EGFR (L858R/T790M): 10 nM; EGFR (wt): 0.5 nM; HER2: 14 nM
Form
Lyophilized powder
Purity
≥98%
Identity
Confirmed by NMR/HPLC/MS.
Applications
BIBW2992 (Afatinib) is used to inhibit EGFR and HER2, useful in clinical cancer research.
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