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EGFR-HER2 inhibitor Canertinib, Purity ≥98%
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Cat. No.: X23-10-ZQ1033

EGFR-HER2 inhibitor Canertinib, Purity ≥98%

Synonym: Canertinib; 267243-28-7; CI-1033; PD-183805; Canertinib free base; N-(4-(3-Chloro-4-fluorophenylamino)-7-(3-morpholinopropoxy)quinazolin-6-yl)acrylamide; N-{4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide; EGFR-HER2 inhibitor

  • CAS Number: 267243-28-7
  • Compound CID: 156414
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Product Size
10 mg; 25 mg; 50 mg; 100 mg; 200 mg
Price
Datasheet
MSDS
Properties
Description
Canertinib, soluble in DMSO and ethanol and insoluble in water, is a potent and specific inhibitor of the tyrosine kinase activity of EGFR. It targets EGFR and ErbB2.
Molecular Weight
485.9
Molecular Formula
C24H25ClFN5O3
Targets
EGFR: 1.5 nM; ErbB2: 9.0 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 2 mg/mL (4.11 mM); Water: Insoluble; Ethanol: 8 mg/mL (16.46 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Canertinib is employed to investigate its inhibitory effects on EGFR family kinases in cancer studies.
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