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EGFR-HER2 inhibitor Lapatinib ditosylate, Purity ≥98%
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Cat. No.: X23-10-ZQ1038

EGFR-HER2 inhibitor Lapatinib ditosylate, Purity ≥98%

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Synonym: Lapatinib Ditosylate; 388082-77-7; Tykerb; Tykerb Ditosylate; Lapatinib (ditosylate); Lapatinib (GW-572016) Ditosylate; EGFR-HER2 inhibitor

  • MDL: MFCD09264195
  • CAS Number: 388082-77-7
  • Compound CID: 9941095
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Product Size
25 mg; 50 mg; 100 mg; 200 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Lapatinib ditosylate, soluble in DMSO and insoluble in ethanol and water, is a potent and specific inhibitor of the tyrosine kinase activity of EGFR. It targets EGFR, ErbB4, c-Fms, and C-Raf-1.
Molecular Weight
925.46
Molecular Formula
C43H42ClFN4O10S3
Targets
EGFR: 10.8 nM; ErbB4: 367 nM; c-Fms: >10 μM; C-Raf-1: >10 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 93 mg/mL (100.49 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Lapatinib ditosylate can be used to inhibit both EGFR and HER2 (ErbB2) in cancer research.
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