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EGFR-HER2 inhibitor Lapatinib (free base), Purity ≥98%
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Cat. No.: X23-10-ZQ1061

EGFR-HER2 inhibitor Lapatinib (free base), Purity ≥98%

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Synonym: Lapatinib; 231277-92-2; Lapatinib ditosylate; Tykerb; GW572016; GW 572016; Lapatinib [INN]; EGFR-HER2 inhibitor

  • MDL: MFCD09264194
  • CAS Number: 231277-92-2
  • Compound CID: 208908
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Lapatinib (free base), soluble in DMSO and insoluble in ethanol and water, is a potent and specific inhibitor of the tyrosine kinase activity of EGFR. It targets EGFR, ErbB4, c-Fms, and C-Raf-1.
Molecular Weight
581.1
Molecular Formula
C29H26ClFN4O4S
Targets
EGFR: 10.8 nM; ErbB4: 367 nM; c-Fms: >10 μM; C-Raf-1: >10 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 99 mg/mL (170.37 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Lapatinib (free base) can be used to inhibit EGFR and HER2 in cancer therapy research.
Publications
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