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EGFR-HER2 inhibitor Mubritinib, Purity ≥98%
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Cat. No.: X23-10-ZQ1039

EGFR-HER2 inhibitor Mubritinib, Purity ≥98%

Synonym: Mubritinib; 366017-09-6; Mubritinib (TAK 165); TAK 165; TAK-165; TAK165; (E)-4-((4-(4-(1H-1,2,3-triazol-1-yl)butyl)phenoxy)methyl)-2-(4-(trifluoromethyl)styryl)oxazole; EGFR-HER2 inhibitor

  • MDL: MFCD09954135
  • CAS Number: 366017-09-6
  • Compound CID: 6444692
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Product Size
10 mg; 25 mg; 50 mg; 100 mg; 200 mg
Price
Datasheet
MSDS
Properties
Description
Mubritinib, soluble in DMSO and insoluble in ethanol and water, is a potent and specific inhibitor of the tyrosine kinase activity of EGFR. It targets EGFR, FGFR, BLK, and HER2/ErbB2.
Molecular Weight
468.5
Molecular Formula
C25H23F3N4O2
Targets
EGFR: >25 μM; FGFR: >25 μM; BLK: >25 μM; HER2/ErbB2: 6.0 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 12 mg/mL (25.61 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Mubritinib can be used to inhibit HER2/ErbB2 for research into HER2-positive cancers.
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