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EGFR-HER2 inhibitor Neratinib, Purity ≥98%
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Cat. No.: X23-10-ZQ1040

EGFR-HER2 inhibitor Neratinib, Purity ≥98%

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Synonym: Neratinib; 698387-09-6; HKI-272; Neratinib (HKI-272); Nerlynx; HKI 272; UNII-JJH94R3PWB; EGFR-HER2 inhibitor

  • MDL: MFCD09752958
  • CAS Number: 698387-09-6
  • Compound CID: 9915743
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Neratinib, soluble in warmed DMSO and insoluble in water and ethanol, is a potent and specific inhibitor of the tyrosine kinase activity of EGFR. It targets EGFR, KDR, Akt, and c-Met.
Molecular Weight
557
Molecular Formula
C30H29ClN6O3
Targets
EGFR: 92 nM; KDR: 800 nM; Akt: >20 μM; c-Met: >35 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 4 mg/mL (7.18 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Neratinib can be used to irreversibly inhibit HER2 and EGFR for research into HER2-positive breast cancer.
Publications
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