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EGFR-HER2 inhibitor Pelitinib, Purity ≥98%
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Cat. No.: X23-10-ZQ1043

EGFR-HER2 inhibitor Pelitinib, Purity ≥98%

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Synonym: Pelitinib; 257933-82-7; EKB-569; Pelitinib (EKB-569); WAY-EKB 569; EKB 569; 326894-84-2; EGFR-HER2 inhibitor

  • MDL: MFCD09837868
  • CAS Number: 257933-82-7
  • Compound CID: 6445562
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Pelitinib, soluble in DMSO and insoluble in ethanol and water, is a potent and specific inhibitor of the tyrosine kinase activity of EGFR. It targets MEK/ERK, Src, c-Met, and CDK4.
Molecular Weight
467.9
Molecular Formula
C24H23ClFN5O2
Targets
MEK/ERK: 800 nM; Src: 282 nM; c-Met: 4.1 μM; CDK4: >20 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 12 mg/mL (25.64 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Pelitinib can be used to irreversibly inhibit EGFR for oncology research.
Publications
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