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EGFR-HER2 inhibitor PKC 412, Purity ≥98%
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Cat. No.: X23-10-ZQ1067

EGFR-HER2 inhibitor PKC 412, Purity ≥98%

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Synonym: Midostaurin; PKC412; 120685-11-2; Benzoylstaurosporine; Cgp 41251; PKC-412; 4'-N-Benzoylstaurosporine; EGFR-HER2 inhibitor

  • MDL: MFCD00871372
  • CAS Number: 120685-11-2
  • Compound CID: 9829523
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
PKC 412, soluble in DMSO and warmed ethanol and insoluble in water, is a potent and specific inhibitor of the tyrosine kinase activity of EGFR. It targets PKCβ1, PKCγ, c-FGR, and c-Lyn.
Molecular Weight
570.64
Molecular Formula
C35H30N4O4
Targets
PKCβ1: 30 nM; PKCγ: 24 nM; c-FGR: 790 nM; c-Lyn: 4.30 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 90 mg/mL (157.72 mM); Water: Insoluble; Warmed ethanol: 18 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
PKC 412 (Midostaurin) can be used to inhibit multiple kinases, including PKC and FLT3, for cancer research.
Publications
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