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EGFR-HER2 inhibitor SU-5402, Purity ≥98%
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Cat. No.: X23-10-ZQ1060

EGFR-HER2 inhibitor SU-5402, Purity ≥98%

Synonym: 215543-92-3; su5402; SU-5402; SU 5402; 3-[(3-(2-CARBOXYETHYL)-4-METHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE; 3-[4-Methyl-2-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid; EGFR-HER2 inhibitor

  • CAS Number: 215543-92-3
  • Compound CID: 5289418
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
SU-5402, soluble in DMSO and insoluble in ethanol and water, is a potent and specific inhibitor of the tyrosine kinase activity of EGFR. It targets FGFR1, PDGFRβ, and VEGFR2.
Molecular Weight
296.32
Molecular Formula
C17H16N2O3
Targets
FGFR1: 30 nM; PDGFRβ: 510 nM; VEGFR2: 20 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 54 mg/mL (182.23 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
SU-5402 can be used to inhibit receptor tyrosine kinases including FGFR, VEGFR, and PDGFR in cancer research.
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