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EGFR-HER2 inhibitor Tyrphostin AG 879, Purity ≥98%
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Cat. No.: X23-10-ZQ1028

EGFR-HER2 inhibitor Tyrphostin AG 879, Purity ≥98%

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Synonym: Tyrphostin AG 879; 148741-30-4; AG 879; AG-879; AG879; alpha-Cyano-(3,5-di-t-butyl-4-hydroxy)thiocinnamide; Tyrphostin Ag-879; EGFR-HER2 inhibitor

  • CAS Number: 148741-30-4
  • Compound CID: 135419190
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Tyrphostin AG 879, soluble in DMSO and ethanol and insoluble in water, is a potent and specific inhibitor of the tyrosine kinase activity of EGFR. It targets EGFR, HER2-Neu, PDGFR, and Trk.
Molecular Weight
316.5
Molecular Formula
C18H24N2OS
Targets
EGFR: >500 μM; HER2-Neu: 1.0 μM; PDGFR: >100 μM; Trk: 10 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 35 mg/mL (110.59 mM); Water: Insoluble; Ethanol: 3 mg/mL (9.47 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Tyrphostin AG 879 is employed to inhibit ErbB2 receptor tyrosine kinase, relevant in cancer studies.
Publications
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