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Cat. No.: X24-05-ZQ640

EGFR inhibitor, Purity ≥98%

Synonym: 879127-07-8; Epidermal growth factor receptor inhibitor; EGFR-HER2 inhibitor

  • CAS Number: 879127-07-8
  • Compound CID: 9549299
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Product Size
5 mg; 10 mg; 25 mg
Price
Datasheet
MSDS
Properties
Description
EGFR inhibitor, soluble in DMSO, water and ethanol, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR (WT), EGFR (L858R), EGFREGFR(L861Q), and HER4.
Molecular Weight
413.4
Molecular Formula
C21H18F3N5O
Targets
EGFR (WT): 21 nM; EGFR (L858R): 63 nM; EGFREGFR(L861Q): 4 nM; HER4: 7640 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 79 mg/mL (191.09 mM); Water: <1 mg/mL; Ethanol: 2 mg/mL (4.83 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
EGFR inhibitor is a general term for compounds used to block EGFR activity in various cancer research studies.
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