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ERK inhibitor FR 180204, Purity ≥98%
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Cat. No.: X23-10-ZQ862

ERK inhibitor FR 180204, Purity ≥98%

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Synonym: 865362-74-9; FR 180204; FR-180204; ERK inhibitor II; 5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE; 5-(2-Phenylpyrazolo[1,5-a]pyridin-3-yl)-2H-pyrazolo[3,4-c]pyridazin-3-amine; ERK inhibitor

  • MDL: MFCD14585805
  • CAS Number: 865362-74-9
  • Compound CID: 11493598
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
FR 180204, soluble in DMSO and warmed ethanol and insoluble in water, exhibits potent inhibition of ERK kinase. It targets ERK2 and ERK1.
Molecular Weight
327.34
Molecular Formula
C18H13N7
Targets
ERK2: 0.14 μM (Ki); ERK1: 0.31 μM (Ki)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 57 mg/mL (174.13 mM); Water: Insoluble; Warmed ethanol: 2 mg/mL (6.1 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
FR180204 can be applied to investigate the inhibition of ERK1/2 activity in cellular signaling research.
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