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ERK inhibitor Pluripotin, Purity ≥98%
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Cat. No.: X23-10-ZQ866

ERK inhibitor Pluripotin, Purity ≥98%

Synonym: Pluripotin; 839707-37-8; N-(3-(7-(1,3-Dimethyl-1H-pyrazol-5-ylamino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide; SC1(Pluripotin); CHEMBL4213673; N-(3-(7-((1,3-Dimethyl-1H-pyrazol-5-yl)amino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide; ERK inhibitor

  • MDL: MFCD20527253
  • CAS Number: 839707-37-8
  • Compound CID: 12003241
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
Pluripotin, soluble in DMSO and insoluble in ethanol and water, exhibits potent inhibition of ERK kinase. It targets ERK1 and RasGAP.
Molecular Weight
550.5
Molecular Formula
C27H25F3N8O2
Targets
ERK1: 98 nM (Kd); RasGAP: 212 nM (Kd)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 96 mg/mL (174.37 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Pluripotin can be used to maintain the pluripotency of embryonic stem cells via dual inhibition of ERK1/2 and GSK3 pathways.
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