Cat. No.: X23-10-ZQ868
ERK inhibitor GDC0994, Purity ≥98%
Synonym: Ravoxertinib; GDC-0994; 1453848-26-4; GDC0994; (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one; ERK inhibitor
- MDL: MFCD28143918
- CAS Number: 1453848-26-4
- Compound CID: 71727581
Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
GDC0994, soluble in DMSO and ethanol and insoluble in water, exhibits potent inhibition of ERK kinase. It targets ERK2 and ERK1.
Molecular Formula
C21H18ClFN6O2
Targets
ERK2: 0.3 nM; ERK1: 1.1 nM
Solubility
DMSO: 83 mg/mL (188.7 mM); Water: Insoluble; Ethanol: 83 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
GDC0994 can be utilized to explore the therapeutic potential of ERK1/2 inhibition in oncology.
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