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ERK inhibitor GDC0994, Purity ≥98%
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Cat. No.: X23-10-ZQ868

ERK inhibitor GDC0994, Purity ≥98%

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Synonym: Ravoxertinib; GDC-0994; 1453848-26-4; GDC0994; (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one; ERK inhibitor

  • MDL: MFCD28143918
  • CAS Number: 1453848-26-4
  • Compound CID: 71727581
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
GDC0994, soluble in DMSO and ethanol and insoluble in water, exhibits potent inhibition of ERK kinase. It targets ERK2 and ERK1.
Molecular Weight
440.87
Molecular Formula
C21H18ClFN6O2
Targets
ERK2: 0.3 nM; ERK1: 1.1 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 83 mg/mL (188.7 mM); Water: Insoluble; Ethanol: 83 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
GDC0994 can be utilized to explore the therapeutic potential of ERK1/2 inhibition in oncology.
Publications
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