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Cat. No.: X24-06-ZQ174

FLT3 inhibitor AC220, Purity ≥98%

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Synonym: 950769-58-1; FLT3 inhibitor

  • MDL: MFCD18074524
  • CAS Number: 950769-58-1
  • Compound CID: 24889392
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Product Size
5 mg; 10 mg; 50 mg; 200 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AC220, soluble in DMSO and insoluble in ethanol and water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FLT3. It targets FLT3 (ITD) (MV4-11 cells), and FLT3 (WT).
Molecular Weight
560.7
Molecular Formula
C29H32N6O4S
Targets
FLT3 (ITD): 1.1 nM; FLT3 (WT): 4.2 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 29 mg/mL (51.72 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
AC220 acts as a FLT3 inhibitor in leukemia studies, providing insights into the disruption of aberrant cellular signaling.
Publications
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