Cat. No.: X24-06-ZQ188
FLT3 inhibitor PLX3397, Purity ≥98%
Synonym: 1029044-16-3; FLT3 inhibitor; PLX-3397; PLX 3397
- MDL: MFCD28900745
- CAS Number: 1029044-16-3
- Compound CID: 25151352
Product Size
10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
PLX3397, soluble in DMSO and insoluble in ethanol and water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FLT3. It targets CSF-1R, Flt3, and Kit.
Molecular Formula
C20H15ClF3N5
Targets
CSF-1R: 20 nM; Flt3: 160 nM; Kit: 10 nM
Solubility
DMSO: 71 mg/mL (169.93 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
PLX3397 functions as a multi-kinase inhibitor, including FLT3, for research into tumor microenvironment and cancer therapy.
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