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Cat. No.: X24-06-ZQ200

IGF-1R inhibitor BMS-754807, Purity ≥98%

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Synonym: 1001350-96-4; IGF-1R inhibitor; BMS754807; BMS 754807

  • MDL: MFCD18633202
  • CAS Number: 1001350-96-4
  • Compound CID: 24785538
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
BMS-754807, soluble in DMSO and insoluble in ethanol and water, blocks the insulin-like growth factor 1 receptor (IGF-1R) signaling pathway, which plays a crucial role in cell growth and survival. It targets IGF-1R, TrkB, Aurora A, AuroraB, BTK, CDK2E, CSK, FLT3, GSK-3β, HER1, and IKK1.
Molecular Weight
461.5
Molecular Formula
C23H24FN9O
Targets
IGF-1R: 1.8 nM; TrkB: 4.1 nM; AuroraA: 9 nM; AuroraB: 25 nM; BTK: 3.797 μM; CDK2E: 795 μM; CSK: 5 μM; FLT3: 170 nM; GSK-3β: 780 nM; HER1: >50 μM; IKK1: >50 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 86 mg/mL (186.35 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
BMS-754807 is utilized as an IGF-1R inhibitor, which has implications in studying cancer progression and therapy.
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