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IGF-1R inhibitor GSK1904529A, Purity ≥98%
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Cat. No.: X24-06-ZQ284

IGF-1R inhibitor GSK1904529A, Purity ≥98%

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Synonym: 1089283-49-7; IGF-1R inhibitor; GSK-1904529A

  • MDL: MFCD17010271
  • CAS Number: 1089283-49-7
  • Compound CID: 25124816
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
GSK1904529A, soluble in DMSO and insoluble in ethanol and water, blocks the insulin-like growth factor 1 receptor (IGF-1R) signaling pathway, which plays a crucial role in cell growth and survival. It targets B-Raf (V600E), IGF-1R, ActRIIB, Akt1, Akt2, ALK5, ASK1, Aurora A, AuroraB, CaMKK2, and CDK2/CyclinA.
Molecular Weight
852
Molecular Formula
C44H47F2N9O5S
Targets
B-Raf (V600E): >2 μM; IGF-1R: 27 μM; ActRIIB: >10 μM; Akt1: >10 μM; Akt2: >10 μM; ALK5: >10 μM; ASK1: >25 μM; AuroraA: >8 μM; AuroraB: 4 nM; CaMKK2: >10 μM; CDK2/CyclinA: >10 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 120 mg/mL (140.85 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
GSK1904529A is used to investigate IGF-1 receptor blocking and its implications in targeting cancer cell growth.
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