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JAK inhibitor Abrocitinib, Purity ≥98%
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Cat. No.: X23-10-ZQ352

JAK inhibitor Abrocitinib, Purity ≥98%

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Synonym: Abrocitinib; 1622902-68-4; PF-04965842; Cibinqo; N-[cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl]propane-1-sulfonamide; JAK inhibitor

  • MDL: MFCD30187577
  • CAS Number: 1622902-68-4
  • Compound CID: 78323835
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Abrocitinib, soluble in DMSO and insoluble in ethanol and water, is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets JAK1, JAK2, and Tyk2.
Molecular Weight
323.415
Molecular Formula
C14H21N5O2S
Targets
JAK1: 29 nM; JAK2: 803 nM; Tyk2: 1253 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 58 mg/mL (179.34 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Abrocitinib is used to explore JAK1 inhibition for the treatment of autoimmune and inflammatory diseases.
Publications
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