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JAK inhibitor AZ-960, Purity ≥98%
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Cat. No.: X23-10-ZQ356

JAK inhibitor AZ-960, Purity ≥98%

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Synonym: 905586-69-8; AZ-960; AZ 960; AZ960; (S)-5-Fluoro-2-((1-(4-fluorophenyl)ethyl)amino)-6-((5-methyl-1H-pyrazol-3-yl)amino)nicotinonitrile; (S)-5-Fluoro-2-(1-(4-fluorophenyl)ethylamino)-6-(5-methyl-1H-pyrazol-3-ylamino)nicotinonitrile; JAK inhibitor

  • CAS Number: 905586-69-8
  • Compound CID: 25099184
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AZ-960, soluble in DMSO and ethanol and insoluble in water, is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets JAK2 and JAK2.
Molecular Weight
354.4
Molecular Formula
C18H16F2N6
Targets
JAK2: <3 nM; JAK2: 0.45 nM (Ki)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 70 mg/mL (197.54 mM); Water: Insoluble; Ethanol: 3 mg/mL (8.46 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
AZ-960 can be utilized for investigating JAK2 inhibition and its consequent effects on cancer cell proliferation and immune response.
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