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JAK inhibitor JAK/HDAC-IN-1, Purity ≥98%

Cat. No.: X23-10-ZQ325

JAK inhibitor JAK/HDAC-IN-1, Purity ≥98%

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Synonym: 2284621-75-4; JAK/HDAC-IN-1; 6-(4-((5-Chloro-4-((4-chlorophenyl)amino)pyrimidin-2-yl)amino)-1H-pyrazol-1-yl)-N-hydroxyhexanamide; MUN21754; 6-[4-[[5-Chloro-4-(4-chloroanilino)pyrimidin-2-yl]amino]pyrazol-1-yl]-N-hydroxyhexanamide; JAK inhibitor

  • MDL: MFCD32062830
  • CAS Number: 2284621-75-4
  • Compound CID: 138377596
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
JAK/HDAC-IN-1 is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets HDAC, HDAC2, HDAC6, HDAC8, JAK1, JAK2, JAK3, and Tyk2.
Molecular Weight
450.32
Molecular Formula
C19H21Cl2N7O2
Targets
HDAC: 2 nM; HDAC2: 14 nM; HDAC6: 120 nM; HDAC8: 2470 nM; JAK1: 4.8 nM; JAK2: 4 nM; JAK3: 7.4 nM; Tyk2: 49 nM
Form
Lyophilized powder
Purity
≥98%
Identity
Confirmed by NMR/HPLC/MS.
Applications
JAK/HDAC-IN-1 is researched for its dual inhibition of JAK kinases and HDACs, particularly in hematological malignancies.
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Blood Group and Lewis Antigen
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Human Milk Oligosaccharides (HMOs)
Lacto-N-biose (Cat#: XCO0089Q) 2'-Fucosyllactose (Cat#: XCO0091Q) 3-Fucosyllactose (Cat#: XCO0092Q) Lactodifucotetraose (Cat#: XCO0093Q) Lacto-N-triose I (Cat#: XCO0094Q) 3'-Sialyllactose sodium salt (Cat#: XCO0096Q) 6'-Sialyllactose sodium salt (Cat#: XCO0098Q) 3'-Sialyl-3-fucosyllactose (Cat#: XCO0100Q)
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