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JAK inhibitor AZD1480, Purity ≥98%
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Cat. No.: X23-10-ZQ357

JAK inhibitor AZD1480, Purity ≥98%

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Synonym: AZD1480; 935666-88-9; AZD-1480; (S)-5-Chloro-N2-(1-(5-fluoropyrimidin-2-yl)ethyl)-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine; JAK inhibitor

  • CAS Number: 935666-88-9
  • Compound CID: 16659841
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Product Size
5 mg; 10 mg; 50 mg; 200 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AZD1480, soluble in warmed DMSO and insoluble in water and ethanol, is an available JAK small molecule inhibitor with potential antineoplastic activity. It targets JAK2.
Molecular Weight
348.8
Molecular Formula
C14H14ClFN8
Targets
JAK2: 0.26 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 68 mg/mL (194.96 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
AZD1480 is used to study the inhibition of JAK2/STAT3 signaling in cancer, inflammation, and myeloproliferative disorders.
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