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MEK inhibitor AZD6244, Purity ≥98%
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Cat. No.: X23-10-ZQ826

MEK inhibitor AZD6244, Purity ≥98%

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Synonym: Selumetinib; 606143-52-6; AZD6244; ARRY-142886; AZD 6244; 5-[(4-BROMO-2-CHLOROPHENYL)AMINO]-4-FLUORO-N-(2-HYDROXYETHOXY)-1-METHYL-1H-BENZIMIDAZOLE-6-CARBOXAMIDE; MEK inhibitor

  • MDL: MFCD11977472
  • CAS Number: 606143-52-6
  • Compound CID: 10127622
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Product Size
100 mg; 250 mg; 500 mg; 1000 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AZD6244, soluble in DMSO and insoluble in ethanol and water, prevents the phosphorylation and activation of ERK leading to reduced cell proliferation and induced apoptosis in cancerous cells. It targets MEK1.
Molecular Weight
457.7
Molecular Formula
C17H15BrClFN4O3
Targets
MEK1: 14 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 80 mg/mL (174.79 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
AZD6244 (Selumetinib) can be used to study the inhibition of MEK1/2 to analyze its therapeutic effects in treating cancers.
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