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PAK inhibitor, FRAX1036, Purity ≥98%
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Cat. No.: X24-08-YM273

PAK inhibitor, FRAX1036, Purity ≥98%

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Synonym: 1432908-05-8; FRAX-1036; FRAX 1036; 6-[2-Chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-ethyl-2-[2-(1-methylpiperidin-4-yl)ethylamino]pyrido[2,3-d]pyrimidin-7-one

  • CAS Number: 1432908-05-8
  • Compound CID: 71557891
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
FRAX1036, soluble in DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting PAK. It targets the PAK1, PAK2, and PAK4.
Molecular Weight
518.05
Molecular Formula
C28H32ClN7O
Targets
PAK1: 23.3 nM (Ki); PAK2: 72.4 nM (Ki); PAK4: 2.4 μM (Ki)
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: insoluble; Water: insoluble; Ethanol: 17 mg/mL (32.81 mM)
Applications
FRAX1036 is a cytoskeletal signaling inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of cancers by targeting the PAK1 pathway involved in cell proliferation and survival.
Publications
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