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PAK inhibitor, PF-3758309, Purity ≥98%
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Cat. No.: X24-08-YM267

PAK inhibitor, PF-3758309, Purity ≥98%

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Synonym: 898044-15-0; PF-03758309; N-[(1S)-2-(Dimethylamino)-1-phenylethyl]-6,6-dimethyl-3-[(2-methylthieno[3,2-d]pyrimidin-4-yl)amino]-1,4-dihydropyrrolo[3,4-c]pyrazole-5-carboxamide

  • MDL: MFCD18633226
  • CAS Number: 898044-15-0
  • Compound CID: 25227462
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
PF-3758309, soluble in DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting PAK. It targets the PAK1, PAK6, PAK2, and PAK3.
Molecular Weight
490.2
Molecular Formula
C25H30N8OS
Targets
PAK1: 13.7 nM (ki); PAK6: ki: 17.1 nM; PAK2: 190nM; PAK3: 99 nM
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 87 mg/mL (177.32 mM); Water: insoluble; Ethanol: 87 mg/mL (177.32 mM)
Applications
PF-3758309 is a cytoskeletal signaling inhibitor that can be used for its inhibition by PF-3758309 aims to disrupt cancer cell invasion and metastasis.
Publications
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