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PAK inhibitor, LOR-253, Purity ≥98%
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Cat. No.: X24-08-YM271

PAK inhibitor, LOR-253, Purity ≥98%

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Synonym: 916151-99-0; LOR 253; LOR253; APTO-253; 2-(5-Fluoro-2-methyl-1H-indol-3-yl)-1H-imidazo[4,5-f][1,10]phenanthroline

  • CAS Number: 916151-99-0
  • Compound CID: 11960271
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
LOR-253, soluble in DMSO and insoluble in water and ethanol, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting PAK.
Molecular Weight
367.38
Molecular Formula
C22H14FN5
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 72 mg/mL (195.98 mM); Water: insoluble; Ethanol: insoluble
Applications
LOR-253 is a cytoskeletal signaling inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of various cancers and fibrotic diseases by blocking TGF-β signaling, which plays a role in tumor progression and fibrosis.
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