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PAK inhibitor, KPT 9274, Purity ≥98%
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Cat. No.: X24-08-YM272

PAK inhibitor, KPT 9274, Purity ≥98%

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Synonym: 1643913-93-2; ATG-019; (E)-3-(6-Aminopyridin-3-yl)-N-[[5-[4-(4,4-difluoropiperidine-1-carbonyl)phenyl]-7-(4-fluorophenyl)-1-benzofuran-2-yl]methyl]prop-2-enamide

  • MDL: MFCD30207881
  • CAS Number: 1643913-93-2
  • Compound CID: 117779453
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Product Size
2 mg; 5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
KPT 9274, soluble in DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting PAK.
Molecular Weight
610.63
Molecular Formula
C35H29F3N4O3
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 85 mg/mL (139.2 mM); Water: insoluble; Ethanol: 85 mg/mL (139.2 mM)
Applications
KPT 9274 is a cytoskeletal signaling inhibitor that can be used for its ability to inhibit the export of tumor suppressor proteins and other key regulators from the nucleus to the cytoplasm, which can enhance antitumor activity.
Publications
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