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Raf inhibitor AZ304, Purity ≥98%
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Cat. No.: X23-10-ZQ983

Raf inhibitor AZ304, Purity ≥98%

Synonym: 942507-42-8; AZ304; 3-(2-Cyanopropan-2-yl)-N-(3-((7-methoxyquinazolin-4-yl)amino)-4-methylphenyl)benzamide; 3-(2-Cyanopropan-2-yl)-N-[3-[(7-methoxyquinazolin-4-yl)amino]-4-methylphenyl]benzamide; Raf inhibitor

  • MDL: MFCD31812677
  • CAS Number: 942507-42-8
  • Compound CID: 16202218
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
AZ304, soluble in DMSO and ethanol and insoluble in water, blocks a MAPK/ERK signaling pathway. It targets BRAF V600E, BRAFWT, CRAF, and CSF1R.
Molecular Weight
451.53
Molecular Formula
C27H25N5O2
Targets
BRAF V600E: 38 nM; BRAFWT: 79 nM; CRAF: 68 nM; CSF1R: 35 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 81 mg/mL (179.39 mM); Water: Insoluble; Ethanol: 5 mg/mL (11.07 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
AZ304 can be used to study its selective inhibition of mutant BRAF in various cancer models.
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