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Raf inhibitor Sorafenib tosylate, Purity ≥98%
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Cat. No.: X23-10-ZQ935

Raf inhibitor Sorafenib tosylate, Purity ≥98%

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Synonym: Sorafenib tosylate; 475207-59-1; Nexavar; Nexavar(R); Sorafenib tosylate [USAN]; Sorafenib (Tosylate); Raf inhibitor

  • MDL: MFCD08235032
  • CAS Number: 475207-59-1
  • Compound CID: 406563
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Product Size
1 mg; 2 mg; 5 mg; 10 mg; 25 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Sorafenib tosylate, soluble in DMSO and water and insoluble in ethanol, blocks a MAPK/ERK signaling pathway. It targets B-Raf, VEGFR2/Flk1, B-Raf (V599E), and c-Kit.
Molecular Weight
637
Molecular Formula
C21H16ClF3N4O3.C7H8O3S
Targets
B-Raf: 22 nM; VEGFR2/Flk1: 15 nM; B-Raf (V599E): 38 nM; c-Kit: 68 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 114 mg/mL (178.95 mM); Water: <1 mg/mL; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Sorafenib tosylate is widely used in cancer research for its ability to inhibit multiple kinases, including RAF kinase.
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