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Raf inhibitor CEP-32496, Purity ≥98%
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Cat. No.: X23-10-ZQ971

Raf inhibitor CEP-32496, Purity ≥98%

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Synonym: CEP-32496; 1188910-76-0; Agerafenib; CEP 32496; RXDX-105; 1-[3-(6,7-Dimethoxyquinazolin-4-yl)oxyphenyl]-3-[5-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-3-yl]urea; Raf inhibitor

  • MDL: MFCD22124524
  • CAS Number: 1188910-76-0
  • Compound CID: 56846693
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
CEP-32496, soluble in DMSO and insoluble in ethanol and water, blocks a MAPK/ERK signaling pathway. It targets LCK, PDGFRβ, Abl1, and ALK.
Molecular Weight
517.5
Molecular Formula
C24H22F3N5O5
Targets
LCK: 2 nM; PDGFRβ: 2 nM (Kd); Abl1: 3 nM (Kd); ALK: >10 μM (Kd)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 8 mg/mL (15.46 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
CEP-32496 can be utilized to investigate BRAF V600E inhibition and its effects on cancer cells.
Publications
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