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Raf inhibitor Dabrafenib mesylate, Purity ≥98%
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Cat. No.: X23-10-ZQ974

Raf inhibitor Dabrafenib mesylate, Purity ≥98%

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Synonym: Dabrafenib mesylate; 1195768-06-9; Dabrafenib (Mesylate); Taflinar; GSK 2118436B; UNII-B6DC89I63E; GSK-2118436B; Raf inhibitor

  • MDL: MFCD20922872
  • CAS Number: 1195768-06-9
  • Compound CID: 44516822
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Dabrafenib mesylate, soluble in DMSO and ethanol and insoluble in water, blocks a MAPK/ERK signaling pathway. It targets BRAF V600E and CRAF.
Molecular Weight
615.67
Molecular Formula
C24H24F3N5O5S3
Targets
BRAF V600E: 0.6 nM; CRAF: 5 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 96 mg/mL (155.92 mM); Water: Insoluble; Ethanol: 5 mg/mL (8.12 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Dabrafenib mesylate can be used to investigate the inhibition of BRAF V600E and its therapeutic role in melanoma.
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