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Raf inhibitor GW 5074, Purity ≥98%

Cat. No.: X23-10-ZQ964

Raf inhibitor GW 5074, Purity ≥98%

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Synonym: gw5074; 220904-83-6; GW 5074; GW-5074; Raf1 Kinase Inhibitor I; 1233748-60-1; 5-Iodo-3-[(3,5-dibromo-4-hydroxyphenyl)methylene]-2-indolinone; Raf inhibitor

  • MDL: MFCD09971042
  • CAS Number: 220904-83-6
  • Compound CID: 5924208
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
GW 5074, soluble in DMSO and insoluble in ethanol and water, blocks a MAPK/ERK signaling pathway. It targets C-Raf.
Molecular Weight
520.94
Molecular Formula
C15H8Br2INO2
Targets
C-Raf: 9 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 101 mg/mL (193.87 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
GW 5074 can be utilized to inhibit Raf-1 kinase and study its role in the MAPK/ERK pathway.
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