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Raf inhibitor Lifirafenib, Purity ≥98%
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Cat. No.: X23-10-ZQ982

Raf inhibitor Lifirafenib, Purity ≥98%

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Synonym: lifirafenib; Beigene-283; BGB-283; 1446090-79-4; 1446090-77-2; BGB283; Lifirafenib [USAN]; Raf inhibitor

  • CAS Number: 1446090-79-4
  • Compound CID: 89670174
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Lifirafenib, soluble in DMSO and ethanol and insoluble in water, blocks a MAPK/ERK signaling pathway. It targets BRAF V600E, EGFR, and EGFR (L858R/T790M).
Molecular Weight
478.42
Molecular Formula
C25H17F3N4O3
Targets
BRAF V600E: 23 nM; EGFR: 29 nM; EGFR (L858R/T790M): 495 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 86 mg/mL (179.76 mM); Water: Insoluble; Ethanol: 86 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
Lifirafenib can be investigated for its potential to inhibit both RAF and EGFR kinases in tumor cells.
Publications
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