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Raf inhibitor NVP-BHG712, Purity ≥98%
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Cat. No.: X23-10-ZQ953

Raf inhibitor NVP-BHG712, Purity ≥98%

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Synonym: NVP-BHG712; 940310-85-0; 4-Methyl-3-(1-methyl-6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)-N-(3-(trifluoromethyl)phenyl)benzamide; Raf inhibitor

  • MDL: MFCD20272929
  • CAS Number: 940310-85-0
  • Compound CID: 16747388
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
NVP-BHG712, soluble in DMSO and ethanol and insoluble in water, blocks a MAPK/ERK signaling pathway. It targets C-Raf, c-Src, Axl, and c-Abl.
Molecular Weight
503.5
Molecular Formula
C26H20F3N7O
Targets
C-Raf: 0.395 μM; c-Src: 1.266 μM; Axl: >10 μM; c-Abl: 1.667 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 90 mg/mL (178.75 mM); Water: Insoluble; Ethanol: 3 mg/mL (5.95 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
NVP-BHG712 can be used to inhibit EphB4 kinase in research focused on cancer and angiogenesis.
Publications
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