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Raf inhibitor RAF265, Purity ≥98%
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Cat. No.: X23-10-ZQ955

Raf inhibitor RAF265, Purity ≥98%

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Synonym: RAF265; 927880-90-8; CHIR-265; RAF-265; RAF 265; RAF265(CHIR-265); RAF265 (CHIR-265); Raf inhibitor

  • MDL: MFCD16659061
  • CAS Number: 927880-90-8
  • Compound CID: 11656518
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
RAF265, soluble in DMSO and ethanol and insoluble in water, blocks a MAPK/ERK signaling pathway. It targets B-Raf and VEGFR2.
Molecular Weight
518.4
Molecular Formula
C24H16F6N6O
Targets
B-Raf: 3-60 nM; VEGFR2: 30 nM (EC50)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 85 mg/mL (163.96 mM); Water: Insoluble; Ethanol: 28 mg/mL (54.01 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
RAF265 can be used to investigate the inhibition of both RAF and VEGFR in cancer models.
Publications
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