Cat. No.: X23-10-ZQ015
Bcl-2 antagonist BH3I-1, Purity ≥98%
Synonym: 300817-68-9; BH3I-1; 5-[(4-Bromophenyl)methylene]-a-(1-methylethyl)-4-oxo-2-thioxo-3-thiazolidineacetic acid; 2-(5-(4-bromobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)-3-methylbutanoic acid; Bcl-2 antagonist
- CAS Number: 300817-68-9
- Compound CID: 6090108
Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
BH3I-1, soluble in warmed DMSO and warmed ethanol and insoluble in water, specifically inhibits the function of the anti-apoptotic proteins, thereby promoting apoptosis in cancer cells.
Molecular Formula
C15H14BrNO3S2
Solubility
Warmed DMSO: 56 mg/mL (139.89 mM); Water: Insoluble; Warmed ethanol: 11 mg/mL (27.47 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
BH3I-1 can be used to selectively inhibit Bcl-2 to study its effects on apoptosis and its potential as a therapeutic target.
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